Toothbrushing for preventing ventilator-associated pneumonia

on the potential contribution of oral care in preventing ventilator-associated pneumonia (VAP) has led to the generally accepted practice of using oral antiseptic agents [1]; however, the value of toothbrushing remains controversial. Dr Gu and colleagues [2] investigated the eff ect of oral care with versus without toothbrushing on VAP prevention by meta-analysis, and found toothbrushing not to signifi cantly reduce VAP incidence (risk ratio 0.77, 95% confi dence interval 0.50 to 1.21). We feel, however, uncomfortable with the message that '… there is currently a lack of evidence to support toothbrushing in patients receiving mechanical ventilation'. Th is phrase might instigate healthcare professionals to abstain from brushing patients' teeth while the primary objective of tooth-brushing is to maintain oral health, not to prevent VAP. A potential VAP risk reduction should rather be considered as a favorable side eff ect. Also, two studies [3,4] in which VAP diagnosis was exclusively based on a Clinical Pulmonary Infection Score (CPIS) ≥6 were included in the meta-analysis. Th e CPIS is known to have moderate performance as well as considerable interobserver variability, and has been shown not to diff erentiate adequately between patients with VAP and systemic infl ammatory response syndrome [5]. Our concern is well illustrated by Munro et al. [4] reporting to have unexpectedly found 115/192 patients with CPIS ≥6 at day 1 of data collection. Th is diagnostic issue may have yielded a vast overestimation of VAP rates and could have been acknowledged. We encourage researchers to use more stringent defi nitions for VAP diagnosis in future investigations. Competing interests SIB gives lectures on oral care for Kimberley-Clark. SOL gave a one-time presentation on oral care for Kimberley-Clark at the 2011 Annual Congress of the European Society for Intensive Care Medicine, Berlin. SOL held a doctorate research mandate from University College Ghent (2006-2012) and SIB holds a research mandate from the special research fund at Ghent University (Belgium). Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis. Impact of oral care with versus without toothbrushing on the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials. CC: Brushing teeth with purifi ed water to reduce ventilator-associated pneumonia. Diagnosis of ventilator-associated pneumonia: a systematic review of the literature.